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Why Should 25-oh-vitamin D And Hcy Be Tested Together?

Vitamin D deficiency is known to be strongly associated with bone metabolic disease and rickets.


In recent years, there has been increasing evidence that vitamin D deficiency may also lead to an increased risk of cardiovascular disease. Clinical findings show that serum vitamin D concentration is significantly associated with a decreased risk of cardiovascular and cerebrovascular death.


25-OH-VD & HCY


Vitamin D deficiency is also linked to blood-sugar metabolism and can be as high as 60 to 90 percent in people with type 2 diabetes.


Studies have shown that vitamin D can promote the synthesis and secretion of insulin and improve insulin resistance.


Coincidentally, high HCY is also an important risk factor for the occurrence and development of various atherosclerosis, and recent studies have shown that high HCY also attacks pancreatic islet cells and is positively correlated with abnormal glucose metabolism.


25-OH-VD & HCY


Both VD deficiency and high HCY can lead to vascular injury.


The blood sugar problems caused by lack of VD and high HCY also damage our blood vessels.


In recent years, more and more attention has been paid to the combined detection of 25-OH-VD and HCY.


25-OH-VD & HCY

Care for blood vessels, pay attention to blood sugar.


[1] Jared P,Denise M,Erin D,et al.Serum vitamin D,parathy-roidhormone levelsand carotid atherosclerosis[J].NIH Pub-licAccess,2009,207(2):585-590.

[2] Liu J, Xu Y, Ning Z W, et al. Relationship between serum vitamin D level and thyroid function in type 2 diabetes mellitus [J]. Chinese Journal of Endocrinology and Metabolism, 2015,31 (3): 245-248

[3] Grammatiki M,Rapti E,Karras S,Ajjan RA,Kotsa K.VitaminD and diabetes mellitus:Causal or casual association? .Rev Endocr MetabDisord.2017; 18 (2) : 227-241. The doi: 10.1007 / s11154-016-9403 - y.

[4] Li Yongjie, Fu Wei, Liu Ying, et al. A study of plasma homocysteine levels and related factors in elderly patients with infarction [J]. Chin J Geriatric Cardio-Cerebrovascular Disease, 2006,8 (7): 459-461

[5] ZHANG Yao, LU Jumping, GU Weijun, et al. Effects of homocysteine on insulin secretion and apoptosis of pancreatic beta cells [J]. Chinese Journal of Medical Sciences, 2008, 88(14): 990-993. (in Chinese)

[6] XIAO Ji, MA Mingkun, YAN Weili, et al. The relationship between serum homocysteine and insulin resistance in patients with abnormal glucose metabolism [J]. Journal of Clinical Laboratory Medicine, 2013(06): 472-474.


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