Infectious diseases are one of the leading causes of disability and death among children worldwide, accounting for about 15 million deaths worldwide each year. Early, rapid and accurate diagnosis of pathogenic agents of infection and targeted treatment is very important for the prognosis of patients.
In pediatrics, it is difficult for children to collect blood because of fine veins, crying, and non-cooperation during blood collection. Therefore, the method of peripheral blood collection is generally adopted to reduce the pain of blood collection in children. The degree of cooperation of children has been improved, and the pressure of parents and medical staff has also been reduced.
In the burn department, burn patients are usually at high risk for infection. The incidence of severe infection or sepsis infection is high, and the burn area of burn patients is large, the wound is deep, and there are burn scars on the skin surface, so it is difficult to collect blood samples. The peripheral blood collection has the unique advantage of meeting the patient's expectations, which is shown in the extremely high "needle rate" and in line with the patient's psychological acceptance range.
The peripheral blood test has the advantages of convenient operation and safety, not affecting daily function, less pain, less blood collection, and so on.
In order to solve the problem of blood collection for patients with venous blood collection difficulties (such as infants, patients with extensive burns, or patients who need frequent blood collection for examination). Common infection indicators, such as blood routine, C-reactive protein, serum amyloid A and other detection products have realized peripheral blood sampling and detection.
Procalcitonin (PCT), which plays an important role in the diagnosis and treatment of infectious diseases, has always been the focus of clinical attention whether peripheral blood sampling, accurate and rapid detection can be achieved.
A. Procalcitonin (PCT) has been widely used as an important reference index for the diagnosis and treatment of bacterial infectious diseases, and the guiding value of PCT in the course of antimicrobial therapy for patients with lower respiratory tract infection and severe infection in ICU has been gradually recognized.
B. The sensitivity and specificity of PCT in bacterial infection, especially sepsis, were as high as 95%, and the diagnostic specificity of severe sepsis and septic shock was as high as 100%.
C. PCT is an important differentiating index of neonatal sepsis and septic shock.
D. The rational use of antibiotics can be guided according to the level of PCT clinically.
E. When local or slight infection occurs in the body, PCT is not significantly increased; when systemic or severe bacterial infection occurs in the body, PCT is significantly increased, and the degree of increase is positively correlated with the severity of infection.
F. Monitoring indexes of bacterial infection complications in patients undergoing surgery and severe trauma.
Hipro's PCT, to solve the problem of blood collection